Influence of Human Leukocyte Antigen Class II Alleles on Susceptibility toEntamoeba histolyticaInfection in Bangladeshi Children

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Influence of human leukocyte antigen class II alleles on susceptibility to Entamoeba histolytica infection in Bangladeshi children.

BACKGROUND The association of antibody responses with both innate and acquired immunity to amebiasis indicate that CD4+ T cells play a role in protection against Entamoeba histolytica infection. To test this hypothesis, we compared the genotype frequencies of human leukocyte antigen (HLA) class II alleles in a cohort of Bangladeshi children intensively monitored for E. histolytica infection for...

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Human leukocyte antigen class II susceptibility conferring alleles among non-insulin dependent diabetes mellitus patients.

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Human Leukocyte Antigen Class I and II Variants in Yemeni Patients with Chronic Renal Failure

Background: Human leukocyte antigens (HLAs) are found to be significant genetic factors concerning the susceptibility of an individual to certain diseases. Objective: To determine the association between variants of class I (A and B) and class II (DRB1) HLA alleles and chronic renal failure (CRF), compared with healthy controls, in Yemen. Methods: A case-control study in the Urology and Nephrol...

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Background: The Human Leukocyte Antigen (HLA) is the most polymorphic region in human genome. Moreover, HLA haplotype frequencies are largely used in transplantation, the treatment of autoimmune diseases, and population-based studies. The present study aimed to determine HLA-A, -B, -DR alleles and haplotype frequencies in 88 unrelated donors of Iranian Gilak ethnic group, by Polymerase Chain Re...

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ژورنال

عنوان ژورنال: The Journal of Infectious Diseases

سال: 2004

ISSN: 0022-1899,1537-6613

DOI: 10.1086/381272